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Last Updated on 13 November 2011
LifeLines has been very successful in establishing its position as a scientific study and biobank. LifeLines participates in, a.o.:
1. the P3G consortium (www.p3g.org).
This Public Population Project in Genomics (P³G) is a non-for-profit international consortium promoting collaboration between researchers in the field of population genomics. Since its foundation, LifeLines has been an active member of P3G. This means that many of the LifeLines questionnaires have been harmonized and standardized on the basis of P3G best practices.
2. BBMRI-Europe.
This Biobanking and Biomolecular Resources Research Infrastructure is a pan-European and internationally broadly accessible research infrastructure and a network of existing and de novo biobanks and biomolecular resources. The infrastructure includes samples from patients and healthy persons, representing different European populations (with links to epidemiological and health care information), molecular genomic resources and biocomputational tools to optimally exploit this resource for global biomedical research. As a follow-up project, the scientific BioShaRE project (funded in KP7 with 12 mill. Euro) aims to develop and apply methods and tools that will provide a foundation for an ambitious program of harmonisation and standardisation in European biobanks and major biomedical studies. LifeLines is one of the participating cohorts in BioShaRE-EU, which is led by prof. Ronald Stolk (head of Epidemiology of the UMCG) and Paul Burton (geneticist, Leicester).
3. BBMRI-NL.
This Dutch collaboration of population-based and disease-oriented Biobanks in The Netherlands comprises an array of quality-assessed biobanks with greatly improved accessibility, enriched in a targeted, expert-driven manner to an up-to-date informational content, for maximum utility to the public and private biomedical field, and for optimal integration with larger international activities.
Within BBMRI-NL, LifeLines is actively participating in several collaborations, amongst others in projects devoited to biomarkers, gene expression, harmonization and standardization, and nutrition.
4. Ti-Pharma.
Top Institute Pharma (TI Pharma) is a public-private partnership in which scientific and business worlds work together on groundbreaking, multidisciplinary research aimed at improving the development of socially valuable medicines. This research precedes the stage in which companies develop individual medicines commercially. Our institute acts as an essential link in combining the knowledge present in science and industry. Collaboration within our research projects provides unique opportunities to strengthen the scientific foundation of pharmaceutical research in the Netherlands.
Within TIPharma, the Mondriaan project -in which LifeLines is participating- aims to develop “A grid to integrate and to enrich existing and new health data platforms in order to fuel pharmaceutical research in The Netherlands and to play an internationally competitive role in drug intelligence and innovation”. Existing databases in the Netherlands will be combined into a common framework; to analyze and update/optimize existing collection of data and acquire new access to health care data; to find optimal technological solutions for access, protection and storage of health care data either at a single or multiple locations; to design a structure to make best scientific use of the data both for academic and industrial partners. New methods and techniques will be established to utilize data from various sources such as GP electronic charts, hospital discharge data, pharmacies, etc.
5. Ti-Food and Nutrition.
Top Institute (TI) Food and Nutrition is a unique public/private partnership that generates scientific breakthroughs in food and nutrition. This results in the development of innovative products and technologies that respond to consumer demands for safe, tasty and healthy foods. Activities have started to join TiFN with specific projects related to nutrition and multifactorial diseases.
6. NCHA, National Consortium on Healthy Ageing.
The Netherlands Consortium for Healthy Ageing (NCHA) originally was an alliance between the Leiden University Medical Centre, the Erasmus Medical Centre, Unilever, Philips Healthcare, Galápagos and McRoberts. In its second phase, several other parties joined the consortium, and the UMCG is one of them. Objective of NCHA is the develop a thorough understanding of the (healthy) ageing process and of age-related diseases. It studies interventions that may be applied to protect and preserve health: new ways for prevention, diagnosis, prognosis, treatment and self-management regarding age-related disease.
LifeLines has joined NCHA (http://www.healthy-ageing.nl/) as a full member, with a research focus on (Epi)genomics in age-related diseases in the LifeLines Cohort Study.
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